Androgen Agonists and Antagonists
- Siterone contains cyproterone acetate
- Siterone is available in two strengths – 50 mg or 100 mg
- Siterone 50 mg and Siterone 100 mg are available in blisters of 50 tablets
- Siterone is fully funded on the Pharmaceutical Schedule
Siterone is an antiandrogenic hormone medication containing the active ingredient cyproterone acetate, which is used to treat cancer of the prostate gland. It can also be used in conjunction with other medications or following surgical removal of the testes to treat side effects such as “sweats” or “hot flushes” and to prevent any initial worsening of the disease.
Indications in the man:
Antiandrogen treatment in inoperable carcinoma of the prostate
Reduction of drive in sexual deviations
Indications in the woman
Severe signs of androgenization, e.g. very severe hirsutism in the female, severe androgenetic alopecia, often attended by severe forms of acne and/or seborrhoea.
Siterone, PRESCRIPTION MEDICINE. The active ingredient in each Siterone tablet contains 50 mg or 100 mg cyproterone acetate. Siterone 50 mg and 100 mg tablets are available in blisters of 50 tablets.
Siterone is an antiandrogenic hormone preparation. It inhibits the influence of androgens, which are also produced – to a slight extent- in the female organism, and also exerts a progestational and antigonadotrophic effect. Cyproterone acetate inhibits competitively the effect of androgens at androgen-dependent target organs, e.g. it shields the prostate from the effect of androgens originating from the gonads and/or the adrenal cortex.
In the man, under treatment with Siterone, sexual drive and potency are reduced and gonadal function is inhibited. These changes are reversible following discontinuation of the therapy.
In the woman, hirsuitism is reduced, but also androgen-dependent alopecia and elevated sebaceous gland function are reduced. During treatment, ovarian function is reduced.
Siterone tablets have risks and benefits. Do not use Siterone tablets if you are allergic to cyproterone acetate or any of the other ingredients of Siterone tablets. Discuss with your doctor if you are allergic to any dyes, preservatives, other medication or foods. Please inform your doctor or pharmacist if you are taking or have recently taken any other medicines, including any medicines obtained without a prescription from your pharmacy, health store or supermarket.
Your doctor will inform you of the Siterone tablet dosage you will be required to take each day. Abide by all instructions given by your doctor carefully. Do not change the dosage or stop taking Siterone tablets under any circumstances unless you have approval from your doctor. If you experience any side effects, talk to your doctor or healthcare professional. Discuss with your doctor if you have any concerns.
Siterone tablets are fully funded. Standard doctor’s fees and pharmacy charges apply.
Distributed by REX Medical Ltd, Auckland, New Zealand.
